Clean rooms require meticulous contamination control, precise airflow, pressurisation, and ventilation systems. They must be able to maintain specific temperatures, humidity levels and containment systems. Successful design, construction, and validation of clean rooms relies on establishing an accurate brief and a clear understanding of the flow of people and materials.

Arup has experience desiging clean rooms for a broad range of demands including microelectronics manufacturing, pharmaceutical production and university research. Our engineering services include specialist structural, fire and acoustics design, as well as mechanical, electrical and public health design. All of our clean rooms meet stringent industry standards, including EN ISO 14644 and EU GMP as well as FDE209D.

Our specialists have significant expertise in designing building/process utility systems, including clean steam, clean air systems, industrial gases, vacuum systems and process waters (deionised water, purified water, and water for injection). 

Energy efficiency and decarbonisation is particularly challenging with clean rooms, as they can consume up to one hundred times the energy of a comparably sized commercial structure. Our teams use proven solutions around energy efficiency and management, as well as computational fluid dynamics (CFD) analysis to optimise airflow performance to achieve cleanliness improvements and enhancing effectiveness, all while reducing costs and carbon impact. (CFD can also assist clients meet requirements for airflow, pressurisation, and contamination control strategies.)